https://pubmed.ncbi.nlm.nih.gov/41639986/
Jun 16, 2026 · These findings demonstrate ongoing antigenic drift and the presence of antiviral resistance-associated mutations during the 2024-2025 influenza season, underscoring the need for continued genomic surveillance to guide vaccine and antiviral strategies.
https://academic.oup.com/jid/article/233/6/e1386/8461561
Feb 4, 2026 · We analyzed influenza A virus (IAV) genomes and clinical characteristics from the 2024–2025 season. Whole-genome sequencing was performed on 648 influenza A–positive clinical specimens collected between October 2024 and April 2025.
https://pubmed.ncbi.nlm.nih.gov/42079493/
Oct 31, 2025 · Influenza A (H3N2) variants with a combination of cluster transition site mutations emerged during the NH 2024-2025 season. A further drifted and vaccine-mismatched variant, called subclade K, arose during the SH 2025 season and is projected to predominate among A (H3N2) viruses for the NH 2025-2026 s …
https://utppublishing.com/doi/full/10.3138/jammi-2025-0025
Dec 17, 2025 · During the Northern Hemisphere (NH) 2024–2025 influenza season, A (H3N2) variants emerged with multiple parallel substitutions affecting cluster transition sites 135, 145, 158, and/or 189, with implications for the 2025–2026 season.
https://www.cdc.gov/flu/whats-new/2025-2026-influenza-activity.html
Sep 26, 2025 · Influenza activity in the United States during the 2024–25 season (September 29, 2024 – August 30, 2025) was classified as high severity, marking the most severe influenza season since 2017–18.
https://evidence.nejm.org/doi/full/10.1056/EVIDpha2500069
Dec 17, 2025 · This report describes the influenza viruses circulating during the 2024–2025 influenza season.
https://www.sciencedirect.com/science/article/pii/S0043135425013570
Dec 1, 2025 · Using the time-series data, we investigated the genetic diversity when considering vaccine-relevant sites during the influenza A season 2023/2024. Similar to the analysis for N1, we analyzed H1 mutations by calling mutations and converting nucleotide substitutions to corresponding amino acid changes (see Section 2.4).
https://evidence.nejm.org/doi/pdf/10.1056/EVIDpha2500069
Dec 17, 2025 · This report describes the influ-enza viruses circulating during the 2024–2025 influenza season.
https://jamanetwork.com/journals/jama/fullarticle/2840454
Oct 17, 2025 · Tests of nearly 4 million respiratory specimens revealed that influenza A viruses—A (H1N1)pdm09 and A (H3N2)—were predominant during the season. Influenza B activity was low throughout the season, and no influenza B/Yamagata lineage viruses were detected for the fifth year in a row.
https://www.who.int/emergencies/disease-outbreak-news/item/2025-DON586
Dec 10, 2025 · Since August 2025, there has been a rapid increase of A (H3N2) J.2.4.1 alias K subclade viruses detected from several countries based on available genetic sequence data. These subclade K viruses have several changes from related A (H3N2) viruses.
